Vacation Rentals in Isle of Palms, FL

PRICE PER NIGHT

ACCOMMODATION TYPES

Top-Rated Vacation Rentals in Isle of Palms, FL

Book a vacation rental in Isle of Palms that has the highest visitor rating. Here are 6 of the best vacation rentals in Isle of Palms.
The Palms Retreat, Near Jax Beaches and Mayo Clinic
10

Excellent

·
Isle of Palms
·
4 br
·
Sleeps 10
·
Air Conditioning · On Site Laundry · Wifi ·
From
$1,250/night
Check availability
Property
Apartment · 4 Beds · 3 baths
Amenities
Air Conditioning
On Site Laundry
Wifi
Fireplace
Assigned Parking
Furnished
Other spaces
Kitchen, Workspace
Single level heated pool 5 mins to beach by Mayo
10

Excellent

·
Isle of Palms
·
4 br
·
Sleeps 8
·
Fitness Center · Dishwasher · Wifi ·
From
$376/night
Check availability
Property
House · 4 Beds · 2 baths
Amenities
Fitness Center
Dishwasher
Wifi
Air Conditioning
Furnished
Private Pool
Oven
On Site Laundry
Other spaces
Kitchen, Workspace, Balcony
Price drop
14543 Luth Drive · The Palms Retreat~Firepit~Fenced Yard~Pet Friendly
10

Excellent

·
Isle of Palms
·
4 br
·
Sleeps 10
·
Outdoor Space · Fireplace · Kitchen ·
From
$262/night
Check availability
Property
House · 4 Beds · 3 baths
Amenities
Fireplace
High Ceilings
Oven
Air Conditioning
On Site Laundry
Furnished
Dishwasher
Swimming Pool
Other spaces
Kitchen, Balcony, Workspace
Price drop
Intracoastal Pool Retreat near Beaches+Mayo Clinic
10

Excellent

·
Isle of Palms
·
5 br
·
Sleeps 12
·
Wifi · Furnished · Workspace ·
From
$434/night
Check availability
Property
House · 5 Beds · 2 baths
Amenities
Wifi
Furnished
On Site Laundry
Residents Lounge
Swimming Pool
Air Conditioning
Fireplace
Other spaces
Workspace, Balcony, Kitchen
Breathtaking Views! Intercoastal waterfront home w/pool! 1 mi. from Mayo Clinc
10

Excellent

·
Isle of Palms
·
3 br
·
Sleeps 8
·
Kitchen · Air Conditioning · On Site Laundry ·
From
$306/night
Check availability
Property
House · 3 Beds · 3 baths
Amenities
Air Conditioning
On Site Laundry
Wifi
Furnished
Dishwasher
Fireplace
Private Pool
Fitness Center
Other spaces
Kitchen, Balcony
Price drop
Large Marsh View Home - Near Mayo Clinic and Beaches
10

Excellent

·
Isle of Palms
·
4 br
·
Sleeps 10
·
Beach · Outdoor Space · Air Conditioning ·
From
$329/night
Check availability
Property
House · 4 Beds · 3 baths
Amenities
Beach
Air Conditioning
Wifi
On Site Laundry
Hot Tub
Dishwasher
Furnished
Oven
Other spaces
Kitchen

Budget-Friendly Vacation Rentals in Isle of Palms, FL

Traveling on a budget? We've got you covered. Find a great deal on a vacation rental in Isle of Palms starting at $85. Use the price filter at the top of the page to search for more specific prices.
The Petite Retreat - Walk to Mayo Clinic!
10

Excellent

·
Isle of Palms
·
1 br
·
Sleeps 2
·
In Unit Laundry · Assigned Parking · Dishwasher ·
From
$85/night
Check availability
Property
Apartment · 1 Bed · 1 bath
Amenities
In Unit Laundry
Assigned Parking
Dishwasher
Furnished
Air Conditioning
Wifi
Other spaces
Kitchen
Rent special
Landing Furnished Apartment at Stacey Rd Suites.14359.1382216

No rating

·
Isle of Palms
·
4 br
·
Furnished · Package Service ·
From
$150/night
Min stay: 30 nights
Property
Apartment · 4 Beds · 3 baths
Amenities
Furnished
Package Service
Price drop
Fancy private pool home in Jax beach
10

Excellent

·
Isle of Palms
·
4 br
·
Sleeps 10
·
Dishwasher · Furnished · Pool ·
From
$160/night
Check availability
Property
House · 4 Beds · 2 baths
Amenities
Dishwasher
Furnished
Pool
Wifi
Swimming Pool
Oven
In Unit Laundry
Air Conditioning
Other spaces
Kitchen
The Retreat close to Mayo Clinic!
10

Excellent

·
Isle of Palms
·
3 br
·
Sleeps 6
·
Outdoor Space · Dishwasher · Kitchen ·
From
$160/night
Check availability
Property
House · 3 Beds · 2 baths
Amenities
Dishwasher
In Unit Laundry
Furnished
On Site Laundry
Air Conditioning
Fireplace
Oven
Wifi
Other spaces
Kitchen
Price drop
Mayo Clinic 1.8 miles #2 Your Home Away From Home
10

Excellent

·
Isle of Palms
·
3 br
·
Sleeps 5
·
In Unit Laundry · Air Conditioning · Furnished ·
From
$170/night
Check availability
Property
House · 3 Beds · 2 baths
Amenities
In Unit Laundry
Air Conditioning
Furnished
Light Grey Getaway under 2 miles to mayo, 4 miles to the beach
10

Excellent

·
Isle of Palms
·
4 br
·
Sleeps 8
·
Outdoor Space · Dishwasher · Workspace ·
From
$176/night
Check availability
Property
House · 4 Beds · 3 baths
Amenities
Dishwasher
Oven
Air Conditioning
Fitness Center
Furnished
Wifi
Residents Lounge
Wheelchair Accessible
Other spaces
Workspace, Kitchen
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Updated: September 24, 2023