Vacation Rentals in Santee, SC

PRICE PER NIGHT

ACCOMMODATION TYPES

Top-Rated Vacation Rentals in Santee, SC

Book a vacation rental in Santee that has the highest visitor rating. Here are 6 of the best vacation rentals in Santee.
Large 4 Bedroom in Gated Golf Community on scenic cove off Lake Marion with pool
10

Excellent

·
Santee
·
4 br
·
Sleeps 15
·
Waterfront · Oven · Dishwasher ·
From
$282/night
Check availability
Property
House · 4 Beds · 4 baths
Amenities
Waterfront
Oven
Dishwasher
On Site Laundry
Fireplace
Private Pool
Lake
Wifi
Other spaces
Kitchen
Kindred Spirits Retreat at Lake Marion
10

Excellent

·
Santee
·
3 br
·
Sleeps 7
·
Outdoor Space · Lake · Kitchen ·
From
$303/night
Check availability
Property
House · 3 Beds · 3 baths
Amenities
Lake
Wifi
Oven
Air Conditioning
Dishwasher
Furnished
On Site Laundry
Waterfront
Other spaces
Kitchen, Workspace
Executive 2 BR/2 BA Lakefront Corner Suite Condo
10

Excellent

·
Santee
·
2 br
·
Sleeps 8
·
Wifi · Kitchen · Dishwasher ·
From
$215/night
Check availability
Property
Condo · 2 Beds · 2 baths
Amenities
Wifi
Dishwasher
Oven
Furnished
Air Conditioning
Lake
Waterfront
On Site Laundry
Other spaces
Kitchen
Great for fishing, boating, golfing or just relaxing.
10

Excellent

·
Santee
·
3 br
·
Sleeps 8
·
Oven · Swimming Pool · Elevator ·
From
$201/night
Check availability
Property
Condo · 3 Beds · 3 baths
Amenities
Oven
Swimming Pool
Elevator
Pool
On Site Laundry
Dishwasher
Furnished
Other spaces
Balcony, Kitchen
Price drop
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
10

Excellent

·
Santee
·
3 br
·
Sleeps 6
·
Furnished · Oven · Balcony ·
From
$180/night
Check availability
Property
Condo · 3 Beds · 3 baths
Amenities
Furnished
Oven
Air Conditioning
Dishwasher
In Unit Laundry
Wifi
Walk In Closets
Other spaces
Balcony, Kitchen
Serenity at Santee
10

Excellent

·
Santee
·
2 br
·
Sleeps 6
·
Air Conditioning · Dishwasher · Lake ·
From
$230/night
Check availability
Property
Condo · 2 Beds · 2 baths
Amenities
Air Conditioning
Dishwasher
Lake
Furnished
Pool
Wifi
Waterfront
In Unit Laundry

Our Recommended Vacation Rentals in Santee, SC

We analyzed vacation rentals in Santee from many property providers including but not limited to VRBO, Booking.com, Evolve, Blueground and more. We're providing our top recommended offers on the best vacation rentals in Santee to help you find a deal for your next trip.
Lovely Condo w/pool, balcony, and lakeside view!

No rating

·
Santee
·
2 br
·
Sleeps 5
·
Oven · On Site Laundry · Wifi ·
From
$104/night
Check availability
Property
Condo · 2 Beds · 2 baths
Amenities
Oven
On Site Laundry
Wifi
Swimming Pool
Waterfront
Air Conditioning
Furnished
Dishwasher
Other spaces
Kitchen, Balcony
Price drop
Lakeside Bliss: 3BR Suite at Wyndham Lake Marion

No rating

·
Santee
·
3 br
·
Sleeps 10
·
Lake · Swimming Pool · Oven ·
From
$293/night
Check availability
Property
Condo · 3 Beds · 3 baths
Amenities
Lake
Swimming Pool
Oven
Concierge Service
Elevator
Pool
On Site Laundry
Dishwasher
Other spaces
Workspace, Balcony, Kitchen
Price drop
Lakeside Bliss: 3BR Suite at Wyndham Lake Marion

No rating

·
Santee
·
3 br
·
Sleeps 10
·
Oven · Wheelchair Accessible · On Site Laundry ·
From
$293/night
Check availability
Property
Condo · 3 Beds · 3 baths
Amenities
Oven
Wheelchair Accessible
On Site Laundry
Air Conditioning
Wifi
Ceiling Fan
Lake
Swimming Pool
Other spaces
Kitchen, Workspace, Balcony
Price drop
Lakeside Bliss: 3BR Suite at Wyndham Lake Marion

No rating

·
Santee
·
3 br
·
Sleeps 10
·
Furnished · Oven · Air Conditioning ·
From
$293/night
Check availability
Property
Condo · 3 Beds · 3 baths
Amenities
Furnished
Oven
Air Conditioning
Concierge Service
Waterfront
Wheelchair Accessible
Pool
On Site Laundry
Other spaces
Workspace, Balcony, Kitchen
Price drop
Lakeside Bliss: 3BR Suite at Wyndham Lake Marion

No rating

·
Santee
·
3 br
·
Sleeps 10
·
Fitness Center · Ceiling Fan · Wifi ·
From
$303/night
Check availability
Property
Condo · 3 Beds · 3 baths
Amenities
Fitness Center
Ceiling Fan
Wifi
Elevator
Swimming Pool
Concierge Service
Waterfront
Furnished
Other spaces
Kitchen, Workspace, Balcony

Budget-Friendly Vacation Rentals in Santee, SC

Traveling on a budget? We've got you covered. Find a great deal on a vacation rental in Santee starting at $46. Use the price filter at the top of the page to search for more specific prices.
Econo Lodge Santee
5.6

Good

·
Santee
·
1 br
·
Sleeps 4
·
Smoking Allowed · Hardwood Floor · Workspace ·
From
$46/night
Check availability
Property
Hotel · 1 Bed
Amenities
Smoking Allowed
Hardwood Floor
Assigned Parking
Furnished
Wifi
Storage
Air Conditioning
Other spaces
Workspace
Quality Inn & Suites
5.8

Good

·
Santee
·
1 br
·
Sleeps 5
·
Air Conditioning · Business Center · Furnished ·
From
$50/night
Check availability
Property
Hotel · 1 Bed
Amenities
Air Conditioning
Business Center
Furnished
Swimming Pool
On Site Laundry
Pool
Wifi
Wheelchair Accessible
Other spaces
Workspace
Super 8 by Wyndham Santee
6.3

Good

·
Santee
·
1 br
·
Sleeps 4
·
Business Center · Smoking Allowed · Assigned Parking ·
From
$60/night
Check availability
Property
Hotel · 1 Bed
Amenities
Business Center
Smoking Allowed
Assigned Parking
Wheelchair Accessible
Free Parking
Furnished
Wifi
Air Conditioning
Other spaces
Workspace
Travelodge by Wyndham Santee
6.2

Good

·
Santee
·
1 br
·
Sleeps 4
·
Air Conditioning · Free Parking · Workspace ·
From
$60/night
Check availability
Property
Hotel · 1 Bed
Amenities
Air Conditioning
Free Parking
Assigned Parking
Furnished
Swimming Pool
Smoking Allowed
Wheelchair Accessible
Residents Lounge
Other spaces
Workspace
Rodeway Inn Santee I-95
5.4

Good

·
Santee
·
Studio
·
Sleeps 10
·
Outdoor Space · Workspace · Swimming Pool ·
From
$74/night
Check availability
Property
Hotel · Studio
Amenities
Swimming Pool
Residents Lounge
Business Center
Air Conditioning
Furnished
Pool
Free Parking
Wifi
Other spaces
Workspace
Best Western PLUS Santee Inn
8.4

Very good

·
Santee
·
1 br
·
Sleeps 4
·
Swimming Pool · Wheelchair Accessible · On Site Laundry ·
From
$80/night
Check availability
Property
Hotel · 1 Bed
Amenities
Swimming Pool
Wheelchair Accessible
On Site Laundry
Furnished
Wifi
Free Parking
Air Conditioning
Business Center
Other spaces
Workspace
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Updated: September 27, 2023