Vacation Rentals in Seneca, SC

PRICE PER NIGHT

ACCOMMODATION TYPES

Top-Rated Vacation Rentals in Seneca, SC

Book a vacation rental in Seneca that has the highest visitor rating. Here are 6 of the best vacation rentals in Seneca.
NEW Seneca Creek Hideaway Near Clemson and Lake Keowee w Hot Tub and Game Room
10

Excellent

·
Seneca
·
4 br
·
Sleeps 12
·
Furnished · Dishwasher · Residents Lounge ·
From
$935/night
Check availability
Property
Apartment · 4 Beds · 2 baths
Amenities
Furnished
Dishwasher
Residents Lounge
On Site Laundry
Hardwood Floor
Swimming Pool
Carpet
Air Conditioning
Other spaces
Kitchen, Workspace, Balcony
Lake Hartwell Retreat with Dock, Paddleboard and Kayak
10

Excellent

·
Seneca
·
4 br
·
Sleeps 12
·
Dishwasher · Air Conditioning · Waterfront ·
From
$668/night
Check availability
Property
Apartment · 4 Beds · 2 baths
Amenities
Dishwasher
Air Conditioning
Waterfront
In Unit Laundry
Lake
Oven
Wifi
Free Parking
Other spaces
Kitchen
Cozy 3/2 New Home in Seneca and Clemson Area
10

Excellent

·
Seneca
·
3 br
·
Sleeps 6
·
Air Conditioning · Balcony · Oven ·
From
$250/night
Check availability
Property
Apartment · 3 Beds · 2 baths
Amenities
Air Conditioning
Oven
In Unit Laundry
Wifi
Dishwasher
Furnished
Free Parking
Other spaces
Balcony, Kitchen
Quiet Townhouse, Minutes from Clemson & Lake Keowee
10

Excellent

·
Seneca
·
2 br
·
Sleeps 4
·
Kitchen · Air Conditioning · In Unit Laundry ·
From
$128/night
Check availability
Property
House · 2 Beds · 2 baths
Amenities
Air Conditioning
In Unit Laundry
Waterfront
Oven
Fireplace
Furnished
Lake
Wifi
Other spaces
Kitchen
Beautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson
10

Excellent

·
Seneca
·
4 br
·
Sleeps 15
·
Lake · Ski In Ski Out · Wheelchair Accessible ·
From
$483/night
Check availability
Property
House · 4 Beds · 4 baths
Amenities
Lake
Ski In Ski Out
Wheelchair Accessible
Furnished
Dishwasher
Wifi
Fireplace
Waterfront
Other spaces
Kitchen, Balcony
Tiny House/w outdoor cast-iron shower/tub
10

Excellent

·
Seneca
·
1 br
·
Sleeps 4
·
Furnished · In Unit Laundry · Kitchen ·
From
$128/night
Check availability
Property
Apartment · 1 Bed · 2 baths
Amenities
Furnished
In Unit Laundry
Wifi
Oven
Mountains
Other spaces
Kitchen

Our Recommended Vacation Rentals in Seneca, SC

We analyzed vacation rentals in Seneca from many property providers including but not limited to VRBO, Booking.com, Evolve, Blueground and more. We're providing our top recommended offers on the best vacation rentals in Seneca to help you find a deal for your next trip.
Bountyland Cottage - Lake Keowee - Mountains - Clemson University
9.4

Excellent

·
Seneca
·
2 br
·
Sleeps 4
·
On Site Laundry · Dishwasher · Outdoor Space ·
From
$293/night
Check availability
Property
Apartment · 2 Beds · 1 bath
Amenities
On Site Laundry
Dishwasher
Fireplace
Free Parking
Oven
Furnished
Assigned Parking
Swimming Pool
Other spaces
Kitchen, Workspace
Serene Seneca Retreat with Deck about 4 Mi to Clemson!

No rating

·
Seneca
·
3 br
·
Sleeps 8
·
Wifi · Kitchen · Workspace ·
From
$417/night
Check availability
Property
Apartment · 3 Beds · 2 baths
Amenities
Wifi
Free Parking
In Unit Laundry
Air Conditioning
Dishwasher
Oven
Furnished
Fireplace
Other spaces
Kitchen, Workspace
Charming Seneca Home - 3 Mi to Memorial Stadium!

No rating

·
Seneca
·
4 br
·
Sleeps 10
·
Air Conditioning · Oven · Kitchen ·
From
$464/night
Check availability
Property
Apartment · 4 Beds · 2 baths
Amenities
Air Conditioning
Oven
Free Parking
Dishwasher
Furnished
Wifi
Other spaces
Kitchen
Fairfield Inn & Suites Seneca Clemson Univ Area
9

Excellent

·
Seneca
·
1 br
·
Sleeps 2
·
Carpet · Residents Lounge · Wifi ·
From
$145/night
Check availability
Property
Hotel · 1 Bed
Amenities
Carpet
Residents Lounge
Wifi
On Site Laundry
Fitness Center
Furnished
Swimming Pool
Elevator
Other spaces
Workspace

Budget-Friendly Vacation Rentals in Seneca, SC

Traveling on a budget? We've got you covered. Find a great deal on a vacation rental in Seneca starting at $50. Use the price filter at the top of the page to search for more specific prices.
$1,500 - Updated 2 BR Seneca/Clemson Townhouse

No rating

·
Seneca
·
2 br
·
Deck · In Unit Laundry · Furnished ·
From
$50/night
Min stay: 30 nights
Property
House · 2 Beds · 1 bath
Amenities
In Unit Laundry
Furnished
Hardwood Floor
Assigned Parking
Other spaces
Deck
Furnished apartment perfect for short term stay!
10

Excellent

·
Seneca
·
1 br
·
Sleeps 4
·
Air Conditioning · In Unit Laundry · Outdoor Space ·
From
$51/night
Check availability
Property
Apartment · 1 Bed · 1 bath
Amenities
Air Conditioning
In Unit Laundry
Garage Parking
Wheelchair Accessible
Lake
On Site Laundry
Furnished
Wifi
Other spaces
Workspace, Kitchen
Quality Inn Seneca US-123
8

Very good

·
Seneca
·
1 br
·
Sleeps 4
·
Furnished · Residents Lounge · Assigned Parking ·
From
$71/night
Check availability
Property
Hotel · 1 Bed
Amenities
Furnished
Residents Lounge
Assigned Parking
Pool
Business Center
Swimming Pool
Carpet
In Unit Laundry
Other spaces
Workspace
Best Western Seneca-Clemson
8.1

Very good

·
Seneca
·
1 br
·
Sleeps 10
·
Swimming Pool · Workspace · Residents Lounge ·
From
$79/night
Check availability
Property
Hotel · 1 Bed
Amenities
Swimming Pool
Residents Lounge
Pool
Furnished
Air Conditioning
Free Parking
On Site Laundry
Wifi
Other spaces
Workspace
Beautiful home near Clemson

No rating

·
Seneca
·
2 br
·
Sleeps 4
·
In Unit Laundry · Air Conditioning · Furnished ·
From
$99/night
Check availability
Property
House · 2 Beds · 1 bath
Amenities
In Unit Laundry
Air Conditioning
Furnished
Hampton Inn & Suites Seneca-Clemson Area
9

Excellent

·
Seneca
·
1 br
·
Sleeps 4
·
Wifi · Fitness Center · Free Parking ·
From
$109/night
Check availability
Property
Hotel · 1 Bed
Amenities
Wifi
Fitness Center
Free Parking
Residents Lounge
Pool
Smoking Allowed
On Site Laundry
Furnished
Other spaces
Workspace
Expand your search criteria to see more vacation rentals near Seneca.
Home > South-carolina Vacation Rentals > Seneca Vacation Rentals
Updated: October 3, 2023